Diagnostic Reagents
Why Choose Antibody Test ?
February 20 , 2021

Why Choose Antibody Test

Although the English expert from the World Health Organization (WHO) subsequently tested negative, it was not immediately clear if the earlier result was a false positive, or the result of previous infection or a Sars-CoV-2 vaccination.


WILL VACCINATED PEOPLE GET POSITIVE ANTIBODY RESULTS?

It is possible, but not always, experts say. Most vaccines target the “spike” protein on the virus surface to trigger an immune response that could include IgM antibodies.

“We can assume that any Sars-CoV-2 vaccine containing the spike protein will induce IgM and therefore a diagnostic assay designed to detect spike specific IgM will not be able to differentiate vaccination from infection,” said Helen Fletcher, a professor of immunology at the London School of Hygiene & Tropical Medicine.

Published data on Oxford University/AstraZeneca Plc’s Sars-CoV-2 vaccine shows spike protein-triggered IgM is detectable in some people at least 56 days after immunization, Fletcher said.



IS IT POSSIBLE TO USE DIFFERENT ANTIBODY TESTS?

Tests to detect antibodies triggered by non-spike protein can yield negative results for those who got vaccines targeting spike protein, said Jin Dong-Yan, a professor of virology at the University of Hong Kong.

Vaccines targeting spike protein include those from AstraZeneca, Pfizer Inc and its partner BioNTech, and Moderna.



THERE ARE STILLNEED TO BE CLARIFIED

Such tests, But, can be problematic for other types of vaccines, including whole virus-based shots .some experts said.

“Where a person is injected with whole virus-based inactivated Sars-CoV-2 vaccine...there’s a strong chance that the person may also have positive result from non-spike protein IgM antibody tests,” said Ian Jones, a virologist at Britain’s University of Reading.


Hot Products:

COVID-19 Neutralizing Antibody Testing Kit


COVID-19 Neutralizing Antibody Testing Kit



Novel Coronavirus IgG/IgM Antibody Testing Kit



Leave A Message
Leave A Message
If you are interested in our products and want to know more details,please leave a message here,we will reply you as soon as we can.

Home

Products

about

contact