Total Triiodothyronine TT3 Kit Chemiluminescence Immunoassay

Total Triiodothyronine TT3 Kit Chemiluminescence Immunoassay

Brand :Norman

Product origin :Nanjing

Delivery time :Two weeks after payment

Supply capacity :100,000 units/month

Thyroid TT3 Diagnosis Chemiluminescence Immunoassay Kit:
Methodology: Chemiluminescence Immunoassay
Total Triiodothyronine (TT3) Kit (Chemiluminescence Immunoassay) is intended for in vitro quantitative determination of total triiodothyronine (TT3) content in human serum, based on NRM411 system.

Thyroid TT3 Diagnosis Chemiluminescence Immunoassay Kit:

Methodology: Chemiluminescence Immunoassay 

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Total Triiodothyronine (TT3) Kit (Chemiluminescence Immunoassay) is intended for in vitro quantitative determination of total triiodothyronine (TT3) content in human serum, based on NRM411 system.
Triiodothyronine (T3) is a hormone synthesized and secreted by thyroid or produced from its prohormone thyroxine (T4) outside thyroid. Its secretion is regulated by a negative feedback mechanism involving thyroid, pituitary and hypothalamus. In healthy populations, the concentration of T3 is 1/50 of that of T4. 99.7% of the T3 hormone reversibly binds to carrier proteins such as thyroxine-binding globulin (TBG), few albumins and prealbumins, and the rest T3 hormone remains in a free state. T3 is the true hormone. Its effects on target tissues are roughly four times more potent than  those of T4.

Clinical Significance:                                                                                       
Thyroid dysfunction may cause excessive or insufficient secretion of T3. Besides, disorders of pituitary and hypothalamus will affect the secretion of T3 as thyroid function is directly affected by thyroid-stimulating hormone (TSH). The change of T3 concentration is more sensitive than that of T4 in some thyroid diseases. For example, the test of T3 concentration in blood is more helpful for the diagnosis of hyperthyroidism than that of T4. The level of T3 can also be a good measure of the storage of thyroid hormone in the body under the condition of strong stimulation to thyroid.

Test Principle                                                                                       
The assay is a competitive immunoassay for quantitative determination of TT3 concentration based on chemiluminescence immunoassay technology. The Magnetic Microbeads Reagent contains protecting reagents and magnetic microbeads that are coated with biotin labeled T3 antibody. The Antibody Reagent contains the protecting reagents and acridinium ester labeled BSA-T3 conjugate. Auxiliary Reagent contains dissociating agent and protecting reagents. Sample, calibrator or control is mixed with Magnetic Microbeads Reagent, Antibody Reagent and Auxiliary Reagent to form a sandwich complex. After incubation and automatic magnetic separation conducted by the instrument, trigger solutions are added to generate chemiluminescent reaction and the relative light units (RLUs) are measured by a photomultiplier. A proportional relationship presents between the concentration of TT3 in the sample and the RLUs detected by the NRM411 system.

Packages: 100 Tests/Box, 200 Tests/Box.

Storage and Stability:                                                                                      
1. Sealed: Stable until the expiry date when stored at 2-8ºC.
2. Opened: Stable for 4 weeks for reagents. Stable for 1 week after dissolved/opened for solid control material/liquid control material. To ensure the kit's best performance, it is recommended to place opened kits in the refrigerator if it's not going to be used on board during the next 12 hours. 
3. Do not use it beyond the expiration date.

Calibration and Traceability:                                                                                       
1. Calibration: Each batch of kits contains specific calibration information, stored in the Calibration Card. 
2. Traceability: The TT3 assay is traceable to a NIFDC standard reference material (lot No. 150550-201203).

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About us:                                                                                                       
Nanjing Norman Biological Technology Co., Ltd is dedicated to R&D and manufacturing of automated chemiluminescence system. Founded in 2008, Norman biological has been upholding the idea that R&D shapes future, and concentration determines success. Ever since the beginning, Norman has been focusing on developing and manufacturing chemiluminescence and immunofluorescence  reagents.


Norman's manufacture center is located in the Yuhua District and owns an over 2,000m2 GMP-approved clean workshop.The R&D base,which is over 2,000m2,is located in state-level new Jiangbei district.Now there are over 100 R&D engineers, 40% of which hold a PhD or master's degree.

Agent Wanted: If you are interested in working with us, please feel free to contact. 


Why Us:                                                                                                                

1. Manufacturer and Exporter for nearly 10 years with self R&D Research Center;

2. Professional After-Sale service with On-site support worldwide; 
3. CE/ISO13485/SGS/RoHS Certifications!

OEM and ODM are available !

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