CLIA Creatine Kinase Isoenzyme Whole Blood Reagent

CLIA Creatine Kinase Isoenzyme Whole Blood Reagent

Brand :Norman

Product origin :Nanjing

Delivery time :Two weeks after payment

Supply capacity :100,000 units/month

Chemiluminesence Immonoassay Ck MB (Creatine Kinase Isoenzyme) test kits
1. Important indicator for diagnosis of AMI.
2. Analyze re-infarction and infarction size.

Chemiluminesence Immonoassay Ck MB (Creatine Kinase Isoenzyme) Test Reagent:

Methodology: Chemiluminescence immunoassay

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1. Registration No: Jiangsu food and drug administration 2014-2400618.
2. Important indicator for diagnosis of AMI.
3. Analyze  re-infarction and infarction size.

Clinical Significance:                                                                                       
1. Began to rise after 3-8 hrs
2. Reach peak value after 8-24hrs  
3. Return to normal value after 3 days
4. Early diagnosis of AMI and risk stratification .
5. Most valuable markers of non-ST-segment elevation MI
6. CK-MB  mainly exists inmyocardium. Content of CK-MB in serum is sensitive and specific to myocardial damage.
7.CK-BB Mainly exists in brain, prostate,intestine,lung,bladder,uterus,placenta,and goiter.
CK-MM  Mainly exists in skeletal muscle and myocardium.

Product advantage:                                                                                         
1. High sensitivity: 0.4ng/ml.
2. High accuracy : 99% result correlation with similar product of Siemens ADVIA Centaur.
3. Wide linear range: 0.4-300ng/ml.


Intended Use

Creatine Kinase-MB (CK-MB) kit (Fluorescein Enhanced Chemiluminescence Immunoassay) is intended for in vitro quantitative determination of Creatine kinase-MB content in human serum and plasma, based on NRM411 system.

CK-MB is mainly from myocardial tissue. The increased level of CK-MB in serum is a significant indicator of diagnosis of acute myocardial infarction (AMI) and identification of myocardial necrosis. In cases of acute myocardial infarction (AMI), the concentration of CK-MB rises as early as 3 to 6 hours after onset, peaks at between 12 and 24 hours, and returns to normal after 3 days if without any complications. However, if there are complications, the level of the enzyme in the serum will remain high. If MI happens again, the decreased level of CK-MB will rise again, and the curve of the enzyme activity will form saddle pattern.

Principle of the Procedure

The assay is a sandwich immunoassay for quantitative determination of CK-MB concentration based on chemiluminescence immunoassay technology. The Magnetic Microbeads Reagent contains protecting reagents and magnetic beads that are coated with FITC antibody. The Antibody Reagent 1 contains the protecting reagent and acridinium ester labeled specific CK-MB antibody. The Antibody Reagent 2 contains the protecting reagent and FITC labeled CK-MB antibody. Sample, calibrator or control is mixed with Magnetic microbeads Reagent and Antibody Reagent to form a sandwich complex. After incubation and automatic magnetic separation conducted by the instrument, trigger solutions are added to generate chemiluminescent reaction and the RLUs are measured by the photomultiplier. A direct relationship exists between the amount of CK-MB in the sample and the RLUs detected by the NRM411 system.

Company profile:                                                                                             

Nanjing Norman Biological Technology Co., Ltd is dedicated to R&D and manufacturing of automated chemiluminescence system. Founded in 2008, Norman biological has been upholding the idea that R&D shapes future ,and concentration determines success. Ever since the beginning,Norman has been focusing on developing and manufacturing  chemiluminescence and immunofluorescence  reagents.


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Why Us:                                                                                                                

1. Manufacturer and Exporter for nearly 10 years with self R&D Research Center;

2. Professional After-Sale service with On-site support worldwide; 
3. CE/ISO13485/SGS/RoHS Certifications!

OEM and ODM are available !

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